KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACHE
All Species:
19.7
Human Site:
T42
Identified Species:
33.33
UniProt:
P22303
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22303
NP_000656.1
614
67796
T42
E
D
A
E
L
L
V
T
V
R
G
G
R
L
R
Chimpanzee
Pan troglodytes
XP_516857
643
72946
A76
T
E
D
D
I
I
I
A
T
K
N
G
K
V
R
Rhesus Macaque
Macaca mulatta
NP_001121560
614
67754
T42
E
D
A
E
L
L
V
T
V
R
G
G
R
L
R
Dog
Lupus familis
XP_546946
611
67308
T39
E
D
P
E
L
L
V
T
V
R
G
G
R
L
R
Cat
Felis silvestris
Mouse
Mus musculus
P21836
614
68150
R42
E
D
P
Q
L
L
V
R
V
R
G
G
Q
L
R
Rat
Rattus norvegicus
P37136
614
68178
R42
E
D
P
Q
L
L
V
R
V
R
G
G
Q
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505841
602
68511
T35
M
E
E
D
F
V
I
T
T
K
K
G
K
V
R
Chicken
Gallus gallus
P36196
767
83002
T35
N
R
P
E
V
R
T
T
T
G
S
V
R
G
L
Frog
Xenopus laevis
NP_001121332
600
68177
T32
S
D
A
G
L
Q
V
T
T
H
S
G
K
V
R
Zebra Danio
Brachydanio rerio
Q9DDE3
634
71980
A32
A
E
P
D
L
V
V
A
T
R
L
G
R
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07140
649
71767
Q46
V
I
D
R
L
V
V
Q
T
S
S
G
P
V
R
Honey Bee
Apis mellifera
XP_393751
657
73886
T73
D
D
P
L
I
V
Q
T
R
K
G
K
V
R
G
Nematode Worm
Caenorhab. elegans
P38433
620
71415
S36
L
F
G
E
E
V
L
S
Q
T
G
K
P
L
T
Sea Urchin
Strong. purpuratus
XP_782113
508
56946
I9
I
P
D
V
F
L
I
I
L
L
L
V
I
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.9
99.5
92.8
N.A.
88.4
88.5
N.A.
50.6
47.9
59.6
60
N.A.
34.3
39.8
41.2
37.7
Protein Similarity:
100
66.8
99.6
96
N.A.
93
93.6
N.A.
68.2
58
73.4
73.6
N.A.
51.4
56.9
56.9
51.6
P-Site Identity:
100
13.3
100
93.3
N.A.
73.3
73.3
N.A.
20
20
46.6
33.3
N.A.
26.6
20
20
6.6
P-Site Similarity:
100
66.6
100
93.3
N.A.
86.6
86.6
N.A.
66.6
26.6
60
66.6
N.A.
40
46.6
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
22
0
0
0
0
15
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
50
22
22
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
36
22
8
36
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
15
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
0
0
0
0
0
8
50
72
0
15
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
8
8
0
0
15
8
22
8
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
22
8
15
22
0
0
% K
% Leu:
8
0
0
8
58
43
8
0
8
8
15
0
0
43
15
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
8
43
0
0
0
0
0
0
0
0
0
15
0
0
% P
% Gln:
0
0
0
15
0
8
8
8
8
0
0
0
15
0
8
% Q
% Arg:
0
8
0
8
0
8
0
15
8
43
0
0
36
8
65
% R
% Ser:
8
0
0
0
0
0
0
8
0
8
22
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
8
50
43
8
0
0
0
0
8
% T
% Val:
8
0
0
8
8
36
58
0
36
0
0
15
8
36
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _